Symbol
Name
ID

Bmpr2
bone morphogenetic protein receptor type 2
MGI:1095407

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes

Pulmonary arterial medial hypertrophy

Pulmonary aterial intimal fibrosis

Pulmonary venous occlusion

Elevated pulmonary artery pressure

Pulmonary arterial hypertension

Pulmonary arterial hypertension with lack of acute response to NO challenge

Increased pulmonary vascular resistance

Pulmonary artery vasoconstriction

Dyspnea

Exertional dyspnea

Interlobular septal thickening

Centrilobular ground-glass opacification on pulmonary HRCT

Cough

Disease(s) Associated with BMPR2

primary pulmonary hypertension

pulmonary venoocclusive disease 1

Mouse Phenotypes		abnormal lung vasculature morphology	increased lung endothelial cell proliferation	abnormal pulmonary alveolus morphology	respiratory distress
Availability	Mouse Genotype	abnormal lung vasculature morphology	increased lung endothelial cell proliferation	abnormal pulmonary alveolus morphology	respiratory distress
	Bmpr2^tm1Kmi/Bmpr2⁺
	Gt(ROSA)26Sor^{tm1(RNAi:Bmpr2)Dliu}/Gt(ROSA)26Sor⁺
	Tg(Tagln-rtTA)E1Jwst/0 Tg(tetO-Bmpr2*R899X)#Jwst/0
	Bmpr2^tm1.1Enl/Bmpr2^tm1.1Enl Tg(Acvrl1-cre)L1Spo/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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